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Tirzepatide Intermediates
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  • Tirzepatide Intermediates

Tirzepatide Intermediates

Used in the synthesis of therapeutic peptide Tirzepatide

Tirzepatide synthesis requires a series of well-defined intermediates that contribute to the accurate construction of its complex peptide structure. These compounds play an essential role in assembling the specific amino acid sequences and chemical modifications that define the therapeutic properties of Tirzepatide. By enabling precise control over chain length, stereochemistry, and protective group compatibility, these intermediates support both research-scale development and commercial production of this GLP-1/GIP receptor dual agonist.

Fmoc-L-Lys[C₂₀-OtBu-γ-Glu(OtBu)-AEEA-AEEA]-OH
CAS No.: 2915356-76-0
Fmoc-L-Lys[C₂₀-OtBu-γ-Glu(OtBu)-AEEA-AEEA]-OH
  • Packaging 25 kg/fibre drum
  • Applications Intermediate for Tirzepatide synthesis
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tBuO-C₂₀-γ-Glu(AEEA-AEEA-OSu)-OtBu
CAS No.: 1118767-17-1
tBuO-C₂₀-γ-Glu(AEEA-AEEA-OSu)-OtBu
  • Packaging 25 kg/fibre drum
  • Applications Intermediate for Tirzepatide synthesis
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C₂₀-OtBu-γ-Glu(OtBu)-AEEA-AEEA-OH
CAS No.: 1188328-37-1
C₂₀-OtBu-γ-Glu(OtBu)-AEEA-AEEA-OH
  • Packaging 25 kg/fibre drum
  • Applications Intermediate for Tirzepatide synthesis
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C₂₀-γ-Glu(AEEA-AEEA-OSu)-OH
CAS No.: 1188328-38-2
C₂₀-γ-Glu(AEEA-AEEA-OSu)-OH
  • Packaging 25 kg / fibre drum
  • Applications Tirzepatide intermediate
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Boc-Tyr(tBu)-Aib-OH
CAS No.: 2639221-78-4
Boc-Tyr(tBu)-Aib-OH
  • Packaging 25 kg / fibre drum
  • Applications Tirzepatide intermediate
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Fmoc-Ile-Aib-OH
CAS No.: 2171139-20-9
Fmoc-Ile-Aib-OH
  • Packaging 25 kg / fibre drum
  • Applications Tirzepatide intermediate
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Boc-Tyr(tBu)-Aib-Glu(OtBu)-Gly-OH
CAS No.: 2682040-93-1
Boc-Tyr(tBu)-Aib-Glu(OtBu)-Gly-OH
  • Packaging 25 kg/fibre drum
  • Applications Tirzepatide intermediate
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Fmoc-Ala-Pro-OH
CAS No.: 186023-44-9
Fmoc-Ala-Pro-OH
  • Packaging 25 kg / fibre drum
  • Applications Tirzepatide intermediate
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Fmoc-Ser(tBu)-Gly-OH
CAS No.: 81672-17-5
Fmoc-Ser(tBu)-Gly-OH
  • Packaging 25 kg / fibre drum
  • Applications Tirzepatide intermediate
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What are some medical applications of peptide-based drugs?

Peptides are used in treating viral infections such as hepatitis, HIV, and SARS. Some can target cancer cells by binding to specific tumor markers or mimicking signaling molecules. Others are derived from natural sources to address cardiovascular conditions, offering a wide range of therapeutic potential.

How do researchers select amino acids when designing peptides?

Longer peptides tend to be more difficult to purify and synthesize due to lower yield and stability. In these cases, auxiliary amino acids may be added at the ends to improve solubility and handling. For shorter peptides, typically under five residues, adding hydrophobic amino acids can enhance structural integrity and functionality.

What role do bioactive peptides play in the food industry?

Bioactive peptides are gaining popularity in functional food and nutrition sectors. These peptides can help regulate physiological processes, support immune health, and delay the onset of chronic diseases. Common sources include dairy proteins, plant extracts, collagen, and marine or animal-derived peptides.

Discover more about Amino Acids for Cell Culture Media & Peptide Synthesis
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Amino Acids & Derivatives for Cell Culture
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Amino Acids & Derivatives for Peptide Synthesis
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