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L-Tyrosine disodium salt

Amino Acids & Derivatives for Cell Culture

L-Tyrosine disodium salt

Used in cell culture media for supporting cell growth and proliferation

L-Tyrosine disodium salt (CAS 122666-87-9) is a high-purity amino acid derivative (99% min) typically supplied as a light grey to brownish powder. It is widely used in the formulation of cell culture media due to its improved solubility and compatibility with fed-batch processes in biopharmaceutical production. This amino acid is packed in 25 kg fiber drums and requires storage at 2–8°C to maintain optimal stability. Baishixing maintains a monthly output of up to 20 tons, ensuring reliable supply for both industrial-scale manufacturing and research environments.

  • CAS No.: 122666-87-9
  • Molecular Formula: C₉H₁₃NNa₂O₅
  • Purity: 99% min
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  • Appearance Grayish white to tan powder
  • Molecular Weight 261.18 g/mol
  • Density N/A
  • Boiling Point N/A
  • Melting Point N/A
  • Flash Point N/A
  • Packaging 25 kg per fiber drum
  • Storage Conditions Store at 2–8 °C
  • Customs code 2922509099
  • Product Name
    1. L-Tyrosine disodium salt;
    2. L-Tyrosine,disodium salt,dihydrate;
    3. Disodium (2S)-2-amino-3-(4-oxidophenyl)propanoate;
    4. disodium,(2S)-2-amino-3-(4-oxidophenyl)propanoate,dihydrate.
  • Production capacity 20 tons/month
  • Applications Raw material for cell culture media
Amino Acids & Derivatives for Cell Culture
Amino Acids & Derivatives for Cell Culture
Amino Acids & Derivatives for Cell Culture
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CAS No.
  • L-Tyrosine 60-18-4
  • L-Tyrosine disodium salt 122666-87-9
  • N-Acetyl-L-tryptophan 1218-34-4
  • N-Acetyl-DL-tryptophan 87-32-1
  • L-Cystine dihydrochloride 30925-07-6
  • L-Cystine disodium salt monohydrate 199329-53-8
  • L-Cysteine S-sulfate sodium 150465-29-5
  • Phospho-L-tyrosine disodium salt 1610350-91-8
  • L-Aspartic acid monosodium salt monohydrate 323194-76-9
  • Glycylglycine 556-50-3
  • Triglycine 139-13-9
Product Name
CAS No.
  • Ala-Ala-Ala 5874-90-8
  • L-Alanyl-L-cystine 115888-13-6
  • L-Alanyl-L-tyrosine 3061-88-9
  • Glycyl-L-tyrosine 658-79-7
  • Glycyl-L-tyrosine dihydrate 39630-46-1
  • L-Alanyl-L-Glutamine 39537-23-0
  • L-Carnosine 305-84-0
  • Glycyl-L-glutamine monohydrate 13115-71-4
  • N,N'-Di-L-lysyl-L-cystine dihydrochloride 2920735-07-3
  • α-Ketoglutaric acid 328-50-7
Fmoc-L-Lys[Oct-(otBu)-γ-Glu-(otBu)-AEEA-AEEA]-OH
Fmoc-L-Lys[Oct-(otBu)-γ-Glu-(otBu)-AEEA-AEEA]-OH CAS No.: 1662688-20-1
Ste-γ-Glu-AEEA-AEEA-OSU
Ste-γ-Glu-AEEA-AEEA-OSU CAS No.: 1169630-40-3
tBuO-C₁₈-γ-Glu(AEEA-AEEA-OSu)-OtBu
tBuO-C₁₈-γ-Glu(AEEA-AEEA-OSu)-OtBu CAS No.: 166108-71-0
tBuO-Ste-γ-Glu(AEEA-AEEA-OH)-OtBu
tBuO-Ste-γ-Glu(AEEA-AEEA-OH)-OtBu CAS No.: 1118767-16-0
Boc-L-His(Trt)-Aib-OH
Boc-L-His(Trt)-Aib-OH CAS No.: 2061897-68-3
Fmoc-His(Trt)-Aib-OH
Fmoc-His(Trt)-Aib-OH CAS No.: 1446013-13-3
Boc-His(Trt)-Aib-Glu(OtBu)-Gly-OH
Boc-His(Trt)-Aib-Glu(OtBu)-Gly-OH CAS No.: 1890228-73-5
Fmoc-His-Aib-OH TFA
Fmoc-His-Aib-OH TFA CAS No.: 1446013-08-6
Fmoc-Glu(OtBu)-Gly-OH
Fmoc-Glu(OtBu)-Gly-OH CAS No.: 866044-63-5
Fmoc-His-Aib-OH
Fmoc-His-Aib-OH CAS No.: 1446013-07-5
Fmoc-Gly-Arg(Pbf)-OH
Fmoc-Gly-Arg(Pbf)-OH CAS No.: 1048377-78-1
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  • Sherry Wu
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What is L-Tyrosine disodium salt used for in cell culture?

L-Tyrosine Disodium Salt is a highly soluble form of tyrosine, commonly used in cell culture media to ensure efficient amino acid absorption and stable formulation. Its solubility allows easier preparation during feed processes and supports consistent cell growth, making it suitable for large-scale bioproduction and research environments.

What roles do amino acids play in cell culture media?

Amino acids are essential building blocks for protein synthesis and act as key intermediates in numerous metabolic pathways. In cell culture, they are vital for promoting growth, supporting cell division, and maintaining cellular homeostasis. Proper amino acid supplementation ensures high viability, accelerates proliferation, and boosts experimental reproducibility.

How is glycylglycine (a dipeptide) used in the pharmaceutical and biotech industries?

Glycylglycine is commonly used to:

  • Enhance the uptake of amino acids in cell culture environments
  • Support the formulation of specialized medical and nutritional products
  • Serve as a substrate in enzymatic assays for dipeptidase activity
  • Act as an absorption enhancer in oral drug delivery systems to improve bioavailability

Why is S-sulfo-L-cysteine sodium salt added to mammalian cell culture media?

This amino acid derivative is chosen for its excellent solubility at neutral pH, making it suitable for feed strategies during high-density cultivation. It minimizes localized pH shifts and prevents thermal stress during buffer adjustments. Its use improves media preparation efficiency and supports higher protein expression in recombinant systems.

Which amino acids are beneficial for liver support?

  • Branched-chain amino acids (BCAAs) aid in liver regeneration and help manage symptoms of hepatic encephalopathy.
  • Glutamine contributes to gut barrier function and supports amino acid metabolism.
  • Arginine assists in detoxifying ammonia through the urea cycle.
    If you're looking for a formulation to improve liver function, feel free to reach out to our specialists for tailored guidance.

How can cell growth rate and survival be improved in culture?

Supplementing media with L-Tyrosine can help reduce oxidative stress and support healthier cell growth. It is especially important in serum-free or chemically defined media and is widely used in monoclonal antibody production, particularly with CHO and hybridoma cells.

What impact do amino acids have on mammalian cell behavior?

Beyond protein synthesis, amino acids are involved in signal transduction, membrane integrity, and cellular defense. Their metabolic fate influences energy balance, redox status, and the synthesis of critical cellular components, directly affecting cell health, productivity, and adaptability.

What is the role of L-Tyrosine in CHO cell culture?

L-Tyrosine plays a key role in the synthesis of structural proteins and enzymes. In CHO cell media, it enhances biomass production and supports robust cell growth, making it a critical supplement in biopharmaceutical manufacturing where consistent yields are required.

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Amino Acids & Derivatives for Cell Culture
  • L-Tyrosine
  • L-Tyrosine disodium salt
  • N-Acetyl-L-tryptophan
  • N-Acetyl-DL-tryptophan
  • L-Cystine dihydrochloride
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Sherry Wu
info@cd-bsx.com
+86-28-88531548
+86-13730848292