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Side Chain Raw Material
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Side Chain Raw Material

Used in the synthesis of peptides such as Semaglutide and Tirzepatide

Side chain raw materials are important components for the synthesis of modified peptides, especially those designed for therapeutic applications. These side chain raw materials include linkers, spacers such as AEEA (aminoethoxyethoxyacetic acid), and long-chain fatty acid derivatives that are commonly used to modify amino acid side chains. Such modifications improve peptide stability, prolong half-life, and enhance receptor binding. In drugs such as Semaglutide and Tirzepatide, side chain modifications are necessary to achieve controlled release and targeted activity. These compounds are widely used in the development of peptides for metabolic and endocrine disorders, including type 2 diabetes and obesity.
These raw materials can be used in both solid-phase and solution-phase peptide synthesis, making them suitable for everything from lab-scale research to large-scale manufacturing.

AEEA-AEEA
CAS No.: 1143516-05-5
AEEA-AEEA
  • Packaging 25 kg per fibre drum
  • Applications Side chain building block for peptide synthesis, including Semaglutide, Tirzepatide
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AEEA
CAS No.: 134978-97-5
AEEA
  • Packaging 25 kg/fibre drum
  • Applications Side chain building block for peptide synthesis, including Semaglutide, Tirzepatide
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Fmoc-AEEA-OH
CAS No.: 166108-71-0
Fmoc-AEEA-OH
  • Packaging 25 kg/fibre drum
  • Applications Side chain building block for peptide synthesis, including Semaglutide, Tirzepatide
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Fmoc-AEEA-AEEA
CAS No.: 560088-89-3
Fmoc-AEEA-AEEA
  • Packaging 25 kg per fiber drum
  • Applications Side chain intermediate for Semaglutide and Tirzepatide synthesis
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Boc-AEEA-AEEA
CAS No.: 1069067-08-8
Boc-AEEA-AEEA
  • Packaging 25 kg/fibre drum
  • Applications Side chain intermediate for Semaglutide and Tirzepatide synthesis
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18-(tert-Butoxy)-18-oxooctadecanoic acid
CAS No.: 843666-40-0
18-(tert-Butoxy)-18-oxooctadecanoic acid
  • Packaging 25 kg/fibre drum
  • Applications Side chain intermediate for Semaglutide and Tirzepatide synthesis
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20-(tert-Butoxy)-20-oxoicosanoic acid
CAS No.: 683239-16-9
20-(tert-Butoxy)-20-oxoicosanoic acid
  • Packaging 25 kg/fibre drum
  • Applications Side chain intermediate for Semaglutide and Tirzepatide synthesis
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H-Glu-OtBu
CAS No.: 45120-30-7
H-Glu-OtBu
  • Packaging 25 kg per fiber drum
  • Applications Side chain intermediate for Semaglutide, Tirzepatide, and peptide API synthesis
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Fmoc-Lys-OH
CAS No.: 105047-45-8
Fmoc-Lys-OH
  • Packaging 25 kg/fibre drum
  • Applications Side chain intermediate for Semaglutide and Tirzepatide synthesis
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What are some medical applications of peptide-based drugs?

Peptides are used in treating viral infections such as hepatitis, HIV, and SARS. Some can target cancer cells by binding to specific tumor markers or mimicking signaling molecules. Others are derived from natural sources to address cardiovascular conditions, offering a wide range of therapeutic potential.

How do researchers select amino acids when designing peptides?

Longer peptides tend to be more difficult to purify and synthesize due to lower yield and stability. In these cases, auxiliary amino acids may be added at the ends to improve solubility and handling. For shorter peptides, typically under five residues, adding hydrophobic amino acids can enhance structural integrity and functionality.

What role do bioactive peptides play in the food industry?

Bioactive peptides are gaining popularity in functional food and nutrition sectors. These peptides can help regulate physiological processes, support immune health, and delay the onset of chronic diseases. Common sources include dairy proteins, plant extracts, collagen, and marine or animal-derived peptides.

Discover more about Amino Acids for Cell Culture Media & Peptide Synthesis
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Amino Acids & Derivatives for Cell Culture
  • L-Tyrosine
  • L-Tyrosine disodium salt
  • N-Acetyl-L-tryptophan
  • N-Acetyl-DL-tryptophan
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Amino Acids & Derivatives for Peptide Synthesis
  • Side Chain Raw Material
  • Semaglutide Intermediates
  • Tirzepatide Intermediates
  • Other Intermediates
  • General Protected Amino Acids
Raw Materials & Intermediates
  • Pharmaceutical Raw Materials & Intermediates
  • Food Additive Raw Materials & Intermediates
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