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Amino Acids & Derivatives for Cell Culture
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  • Amino Acids & Derivatives for Cell Culture

Amino Acids for Cell Culture

Used in cell culture media for supporting cell growth and proliferation

In cell culture applications, certain amino acids are added or fine-tuned to better support the unique growth and metabolic needs of specific cell lines. These modified or enriched amino acid profiles help improve cell viability, boost protein expression, and reduce the buildup of metabolic waste. They’re particularly useful when working with sensitive or high-performance cells like CHO, HEK293, or hybridomas. By addressing challenges such as oxidative stress or nutrient depletion, these amino acids contribute to more efficient, consistent, and scalable results, especially in fields like biopharma production, vaccine development, and lab-scale research.

L-Tyrosine
CAS No.: 60-18-4
L-Tyrosine
  • Packaging 25 kg per fiber drum
  • Applications Raw material for cell culture media, pharmaceutical intermediates, APIs, and food additives
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L-Tyrosine disodium salt
CAS No.: 122666-87-9
L-Tyrosine disodium salt
  • Packaging 25 kg per fiber drum
  • Applications Raw material for cell culture media
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N-Acetyl-L-tryptophan
CAS No.: 1218-34-4
N-Acetyl-L-tryptophan
  • Packaging 25 kg per fiber drum
  • Applications Raw material for cell culture media
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N-Acetyl-DL-tryptophan
CAS No.: 87-32-1
N-Acetyl-DL-tryptophan
  • Packaging 25 kg per fiber drum
  • Applications Raw material for cell culture media
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L-Cystine dihydrochloride
CAS No.: 30925-07-6
L-Cystine dihydrochloride
  • Packaging 25 kg per fiber drum
  • Applications Raw material for cell culture media
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L-Cystine disodium salt monohydrate
CAS No.: 199329-53-8
L-Cystine disodium salt monohydrate
  • Packaging 25 kg per fiber drum
  • Applications Raw material for cell culture media, especially for suspension culture systems
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L-Cysteine S-sulfate sodium
CAS No.: 150465-29-5
L-Cysteine S-sulfate sodium
  • Packaging 25 kg per fiber drum
  • Applications Raw material for cell culture media
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Phospho-L-tyrosine disodium salt
CAS No.: 1610350-91-8
Phospho-L-tyrosine disodium salt
  • Packaging 25 kg per fiber drum
  • Applications Raw material for cell culture media
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L-Aspartic acid monosodium salt monohydrate
CAS No.: 323194-76-9
L-Aspartic acid monosodium salt monohydrate
  • Packaging 25 kg per fiber drum
  • Applications Raw material for cell culture media
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Glycylglycine
CAS No.: 556-50-3
Glycylglycine
  • Packaging 25 kg per fiber drum
  • Applications Raw material for cell culture media, cosmetic ingredients, API intermediate
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Triglycine
CAS No.: 139-13-9
Triglycine
  • Packaging 25 kg per fibre drum
  • Applications Raw material for cell culture media and active pharmaceutical ingredients (APIs)
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Ala-Ala-Ala
CAS No.: 5874-90-8
Ala-Ala-Ala
  • Packaging 25 kg per fiber drum
  • Applications Cell culture media ingredient, active pharmaceutical ingredient (API)
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L-Alanyl-L-cystine
CAS No.: 115888-13-6
L-Alanyl-L-cystine
  • Packaging 25 kg per fiber drum
  • Applications Raw material for cell culture media, API intermediate
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L-Alanyl-L-tyrosine
CAS No.: 3061-88-9
L-Alanyl-L-tyrosine
  • Packaging 25 kg per fiber drum
  • Applications Cell culture media (chemically defined), API raw material
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Glycyl-L-tyrosine
CAS No.: 658-79-7
Glycyl-L-tyrosine
  • Packaging 25 kg per fiber drum
  • Applications Cell culture media ingredient, API intermediate
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Glycyl-L-tyrosine dihydrate
CAS No.: 39630-46-1
Glycyl-L-tyrosine dihydrate
  • Packaging 25 kg per fiber drum
  • Applications Cell culture media component
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L-Alanyl-L-Glutamine
CAS No.: 39537-23-0
L-Alanyl-L-Glutamine
  • Packaging 25 kg per fiber drum
  • Applications Cell culture media component
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L-Carnosine
CAS No.: 305-84-0
L-Carnosine
  • Packaging 25 kg per fiber drum
  • Applications Cell culture media raw material
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Glycyl-L-glutamine monohydrate
CAS No.: 13115-71-4
Glycyl-L-glutamine monohydrate
  • Packaging 25 kg per fiber drum
  • Applications Cell culture media raw material
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N,N'-Di-L-lysyl-L-cystine dihydrochloride
CAS No.: 2920735-07-3
N,N'-Di-L-lysyl-L-cystine dihydrochloride
  • Packaging 25 kg per fiber drum
  • Applications Cell culture media material
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α-Ketoglutaric acid
CAS No.: 328-50-7
α-Ketoglutaric acid
  • Packaging 25 kg per fiber drum
  • Applications Cell culture media material
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What roles do amino acids play in cell culture media?

Amino acids are essential building blocks for protein synthesis and act as key intermediates in numerous metabolic pathways. In cell culture, they are vital for promoting growth, supporting cell division, and maintaining cellular homeostasis. Proper amino acid supplementation ensures high viability, accelerates proliferation, and boosts experimental reproducibility.

How is glycylglycine (a dipeptide) used in the pharmaceutical and biotech industries?

Glycylglycine is commonly used to:

  • Enhance the uptake of amino acids in cell culture environments
  • Support the formulation of specialized medical and nutritional products
  • Serve as a substrate in enzymatic assays for dipeptidase activity
  • Act as an absorption enhancer in oral drug delivery systems to improve bioavailability

Why is S-sulfo-L-cysteine sodium salt added to mammalian cell culture media?

This amino acid derivative is chosen for its excellent solubility at neutral pH, making it suitable for feed strategies during high-density cultivation. It minimizes localized pH shifts and prevents thermal stress during buffer adjustments. Its use improves media preparation efficiency and supports higher protein expression in recombinant systems.

Which amino acids are beneficial for liver support?

  • Branched-chain amino acids (BCAAs) aid in liver regeneration and help manage symptoms of hepatic encephalopathy.
  • Glutamine contributes to gut barrier function and supports amino acid metabolism.
  • Arginine assists in detoxifying ammonia through the urea cycle.
    If you're looking for a formulation to improve liver function, feel free to reach out to our specialists for tailored guidance.

How can cell growth rate and survival be improved in culture?

Supplementing media with L-Tyrosine can help reduce oxidative stress and support healthier cell growth. It is especially important in serum-free or chemically defined media and is widely used in monoclonal antibody production, particularly with CHO and hybridoma cells.

What impact do amino acids have on mammalian cell behavior?

Beyond protein synthesis, amino acids are involved in signal transduction, membrane integrity, and cellular defense. Their metabolic fate influences energy balance, redox status, and the synthesis of critical cellular components, directly affecting cell health, productivity, and adaptability.

What is the role of L-Tyrosine in CHO cell culture?

L-Tyrosine plays a key role in the synthesis of structural proteins and enzymes. In CHO cell media, it enhances biomass production and supports robust cell growth, making it a critical supplement in biopharmaceutical manufacturing where consistent yields are required.

Discover more about Amino Acids for Cell Culture Media & Peptide Synthesis
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Amino Acids & Derivatives for Cell Culture
  • L-Tyrosine
  • L-Tyrosine disodium salt
  • N-Acetyl-L-tryptophan
  • N-Acetyl-DL-tryptophan
  • L-Cystine dihydrochloride
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Amino Acids & Derivatives for Peptide Synthesis
  • Side Chain Raw Material
  • Semaglutide Intermediates
  • Tirzepatide Intermediates
  • Other Intermediates
  • General Protected Amino Acids
Raw Materials & Intermediates
  • Pharmaceutical Raw Materials & Intermediates
  • Food Additive Raw Materials & Intermediates
  • Agricultural Raw Materials & Intermediates
  • Cosmetic Raw Materials & Intermediates
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Sherry Wu
info@cd-bsx.com
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