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L-Tyrosine

Amino Acids & Derivatives for Cell Culture

L-Tyrosine

Used in cell culture media for supporting cell growth and proliferation

L-Tyrosine (CAS No. 60-18-4) is a high-purity amino acid (99% min) that appears as a white crystalline powder. It is commonly used as a supplement in cell culture media to support protein synthesis and maintain nutrient balance in mammalian cell lines such as CHO and HEK293. This amino acid is typically included in standard formulations like MEM, DMEM, and RPMI, helping improve cell viability and culture performance, especially under oxidative stress. Beyond its application in cell culture, L-Tyrosine is also used in the production of pharmaceutical intermediates, APIs, and nutritional products due to its biochemical relevance as a precursor to neurotransmitters like dopamine.

  • CAS No.: 60-18-4
  • Molecular Formula: C₉H₁₁NO₃
  • Purity: 99% min
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  • Appearance White crystalline powder
  • Molecular Weight 181.19 g/mol
  • Density 1.3 ± 0.1 g/cm³
  • Boiling Point 385.2 ± 32.0 °C at 760 mmHg
  • Melting Point >>300 °C (decomposition, literature)
  • Flash Point 186.7±25.1 °C
  • Packaging 25 kg per fiber drum
  • Stocking Term Store below +30°C.
  • Customs code 2922509099
  • Product Name
    1. L-tyrosine
    2. (S)-Tyrosine
    3. p-Tyrosine
    4. H-Tyr-OH
    5. L-p-Tyrosine
    6. (2S)-2-amino-3-(4-hydroxyphenyl)propanoic acid
    7. 4-Hydroxy-L-phenylalanine
  • Production capacity 10 tons/month
  • Applications Raw material for cell culture media, pharmaceutical intermediates, APIs, and food additives
Amino Acids & Derivatives for Cell Culture
Amino Acids & Derivatives for Cell Culture
Amino Acids & Derivatives for Cell Culture
  • Related Amino Acids
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Product Name
CAS No.
  • L-Tyrosine 60-18-4
  • L-Tyrosine disodium salt 122666-87-9
  • N-Acetyl-L-tryptophan 1218-34-4
  • N-Acetyl-DL-tryptophan 87-32-1
  • L-Cystine dihydrochloride 30925-07-6
  • L-Cystine disodium salt monohydrate 199329-53-8
  • L-Cysteine S-sulfate sodium 150465-29-5
  • Phospho-L-tyrosine disodium salt 1610350-91-8
  • L-Aspartic acid monosodium salt monohydrate 323194-76-9
  • Glycylglycine 556-50-3
  • Triglycine 139-13-9
Product Name
CAS No.
  • Ala-Ala-Ala 5874-90-8
  • L-Alanyl-L-cystine 115888-13-6
  • L-Alanyl-L-tyrosine 3061-88-9
  • Glycyl-L-tyrosine 658-79-7
  • Glycyl-L-tyrosine dihydrate 39630-46-1
  • L-Alanyl-L-Glutamine 39537-23-0
  • L-Carnosine 305-84-0
  • Glycyl-L-glutamine monohydrate 13115-71-4
  • L-Tyrosine 2920735-07-3
  • α-Ketoglutaric acid 328-50-7
AEEA-AEEA
AEEA-AEEA CAS No.: 1143516-05-5
AEEA
AEEA CAS No.: 134978-97-5
Fmoc-AEEA-OH
Fmoc-AEEA-OH CAS No.: 166108-71-0
Fmoc-AEEA-AEEA
Fmoc-AEEA-AEEA CAS No.: 560088-89-3
Boc-AEEA-AEEA
Boc-AEEA-AEEA CAS No.: 1069067-08-8
18-(tert-Butoxy)-18-oxooctadecanoic acid
18-(tert-Butoxy)-18-oxooctadecanoic acid CAS No.: 843666-40-0
20-(tert-Butoxy)-20-oxoicosanoic acid
20-(tert-Butoxy)-20-oxoicosanoic acid CAS No.: 683239-16-9
H-Glu-OtBu
H-Glu-OtBu CAS No.: 45120-30-7
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We’re here to support your needs in derivatives and amino acids for cell culture and peptide synthesis.

  • info@cd-bsx.com
  • Sherry Wu
  • +86-13730848292

What roles do amino acids play in cell culture media?

Amino acids are essential building blocks for protein synthesis and act as key intermediates in numerous metabolic pathways. In cell culture, they are vital for promoting growth, supporting cell division, and maintaining cellular homeostasis. Proper amino acid supplementation ensures high viability, accelerates proliferation, and boosts experimental reproducibility.

How is glycylglycine (a dipeptide) used in the pharmaceutical and biotech industries?

Glycylglycine is commonly used to:

  • Enhance the uptake of amino acids in cell culture environments
  • Support the formulation of specialized medical and nutritional products
  • Serve as a substrate in enzymatic assays for dipeptidase activity
  • Act as an absorption enhancer in oral drug delivery systems to improve bioavailability

Why is S-sulfo-L-cysteine sodium salt added to mammalian cell culture media?

This amino acid derivative is chosen for its excellent solubility at neutral pH, making it suitable for feed strategies during high-density cultivation. It minimizes localized pH shifts and prevents thermal stress during buffer adjustments. Its use improves media preparation efficiency and supports higher protein expression in recombinant systems.

Which amino acids are beneficial for liver support?

  • Branched-chain amino acids (BCAAs) aid in liver regeneration and help manage symptoms of hepatic encephalopathy.
  • Glutamine contributes to gut barrier function and supports amino acid metabolism.
  • Arginine assists in detoxifying ammonia through the urea cycle.
    If you're looking for a formulation to improve liver function, feel free to reach out to our specialists for tailored guidance.

How can cell growth rate and survival be improved in culture?

Supplementing media with L-Tyrosine can help reduce oxidative stress and support healthier cell growth. It is especially important in serum-free or chemically defined media and is widely used in monoclonal antibody production, particularly with CHO and hybridoma cells.

What impact do amino acids have on mammalian cell behavior?

Beyond protein synthesis, amino acids are involved in signal transduction, membrane integrity, and cellular defense. Their metabolic fate influences energy balance, redox status, and the synthesis of critical cellular components, directly affecting cell health, productivity, and adaptability.

What is the role of L-Tyrosine in CHO cell culture?

L-Tyrosine plays a key role in the synthesis of structural proteins and enzymes. In CHO cell media, it enhances biomass production and supports robust cell growth, making it a critical supplement in biopharmaceutical manufacturing where consistent yields are required.

Raw Materials & Intermediates
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Cosmetic Raw Materials & Intermediates Cosmetic Raw Materials & Intermediates
Amino Acids & Derivatives for Cell Culture
  • L-Tyrosine
  • L-Tyrosine disodium salt
  • N-Acetyl-L-tryptophan
  • N-Acetyl-DL-tryptophan
  • L-Cystine dihydrochloride
  • View More
Amino Acids & Derivatives for Peptide Synthesis
  • Side Chain Raw Material
  • Semaglutide Intermediates
  • Tirzepatide Intermediates
  • Other Intermediates
  • General Protected Amino Acids
Raw Materials & Intermediates
  • Pharmaceutical Raw Materials & Intermediates
  • Food Additive Raw Materials & Intermediates
  • Agricultural Raw Materials & Intermediates
  • Cosmetic Raw Materials & Intermediates
Contact Us
Sherry Wu
info@cd-bsx.com
+86-28-88531548
+86-13730848292