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  • Fmoc-AEEA-OH
Fmoc-AEEA-OH

Amino Acids & Derivatives for Peptide Synthesis

Fmoc-AEEA-OH

Used in the synthesis of peptides such as Semaglutide and Tirzepatide

Fmoc-AEEA-OH (CAS No. 166108-71-0, molecular formula C₂₁H₂₃NO₆) is a white to beige solid used in peptide synthesis as a hydrophilic spacer with an Fmoc-protected amino group. It allows controlled chain extension during solid-phase synthesis and is commonly used in the preparation of GLP-1 receptor agonists such as Semaglutide and Tirzepatide. The compound is supplied in 25 kg fiber drums and should be stored under inert atmosphere at room temperature to ensure stability.

  • CAS No.: 166108-71-0
  • Molecular Formula: C₂₁H₂₃NO₆
  • Purity: 99% min
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  • Appearance White to beige solid
  • Molecular Weight 385.4 g/mol
  • Density N/A
  • Boiling Point N/A
  • Melting Point N/A
  • Flash Point N/A
  • Packaging 25 kg/fibre drum
  • Customs Code 2921199990
  • Storage Conditions Store at room temperature under inert atmosphere
  • Product Name
    1. Fmoc-AEEA-OH; [2-[2-(Fmoc-amino)ethoxy]ethoxy]acetic acid
  • Monthly Production Capacity 2 tons/month
  • Applications Side chain building block for peptide synthesis, including Semaglutide, Tirzepatide
Amino Acids & Derivatives for Peptide Synthesis
Amino Acids & Derivatives for Peptide Synthesis
Amino Acids & Derivatives for Peptide Synthesis
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Product Name
CAS No.
  • AEEA-AEEA 1143516-05-5
  • AEEA 134978-97-5
  • Fmoc-AEEA-OH 166108-71-0
  • Fmoc-AEEA-AEEA 560088-89-3
  • Boc-AEEA-AEEA 1069067-08-8
Product Name
CAS No.
  • 18-(tert-Butoxy)-18-oxooctadecanoic acid 843666-40-0
  • 20-(tert-Butoxy)-20-oxoicosanoic acid 683239-16-9
  • H-Glu-OtBu 45120-30-7
  • Fmoc-Lys-OH 105047-45-8
Boc-L-His(Trt)-Aib-OH
Boc-L-His(Trt)-Aib-OH CAS No.: 2061897-68-3
Fmoc-His(Trt)-Aib-OH
Fmoc-His(Trt)-Aib-OH CAS No.: 1446013-13-3
Boc-His(Trt)-Aib-Glu(OtBu)-Gly-OH
Boc-His(Trt)-Aib-Glu(OtBu)-Gly-OH CAS No.: 1890228-73-5
Fmoc-His-Aib-OH TFA
Fmoc-His-Aib-OH TFA CAS No.: 1446013-08-6
Fmoc-Glu(OtBu)-Gly-OH
Fmoc-Glu(OtBu)-Gly-OH CAS No.: 866044-63-5
Fmoc-His-Aib-OH
Fmoc-His-Aib-OH CAS No.: 1446013-07-5
Fmoc-Gly-Arg(Pbf)-OH
Fmoc-Gly-Arg(Pbf)-OH CAS No.: 1048377-78-1
Fmoc-L-Lys[Oct-(otBu)-γ-Glu-(otBu)-AEEA-AEEA]-OH
Fmoc-L-Lys[Oct-(otBu)-γ-Glu-(otBu)-AEEA-AEEA]-OH CAS No.: 1662688-20-1
Ste-γ-Glu-AEEA-AEEA-OSU
Ste-γ-Glu-AEEA-AEEA-OSU CAS No.: 1169630-40-3
tBuO-C₁₈-γ-Glu(AEEA-AEEA-OSu)-OtBu
tBuO-C₁₈-γ-Glu(AEEA-AEEA-OSu)-OtBu CAS No.: 166108-71-0
tBuO-Ste-γ-Glu(AEEA-AEEA-OH)-OtBu
tBuO-Ste-γ-Glu(AEEA-AEEA-OH)-OtBu CAS No.: 1118767-16-0
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What are some medical applications of peptide-based drugs?

Peptides are used in treating viral infections such as hepatitis, HIV, and SARS. Some can target cancer cells by binding to specific tumor markers or mimicking signaling molecules. Others are derived from natural sources to address cardiovascular conditions, offering a wide range of therapeutic potential.

How do researchers select amino acids when designing peptides?

Longer peptides tend to be more difficult to purify and synthesize due to lower yield and stability. In these cases, auxiliary amino acids may be added at the ends to improve solubility and handling. For shorter peptides, typically under five residues, adding hydrophobic amino acids can enhance structural integrity and functionality.

What role do bioactive peptides play in the food industry?

Bioactive peptides are gaining popularity in functional food and nutrition sectors. These peptides can help regulate physiological processes, support immune health, and delay the onset of chronic diseases. Common sources include dairy proteins, plant extracts, collagen, and marine or animal-derived peptides.

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