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  • AEEA-AEEA
AEEA-AEEA

Amino Acids & Derivatives for Peptide Synthesis

AEEA-AEEA

Used in the synthesis of peptides such as Semaglutide and Tirzepatide

AEEA-AEEA (CAS No. 1143516-05-5, molecular formula C₁₂H₂₄N₂O₇) is a white solid used as a flexible spacer in peptide synthesis, especially in compounds like Semaglutide and Tirzepatide. Formed by two AEEA units, it improves solubility, structural spacing, and stability without interfering with peptide activity. It is supplied in 25 kg drums, with a monthly production capacity of 300 kg, and should be stored in a dry environment at 20 °C under inert gas to preserve quality.

  • CAS No.: 1143516-05-5
  • Molecular Formula: C₁₂H₂₄N₂O₇
  • Purity: 99% min
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  • Appearance White to off-white solid
  • Molecular Weight 308.33 g/mol
  • Density 1.202 ± 0.06 g/cm³
  • Boiling Point 548.7 ± 50.0 °C (predicted)
  • Melting Point 133–135 °C
  • Flash Point Not applicable
  • Packaging 25 kg per fiber drum
  • Storage Conditions Store at 20 °C in dry conditions, under inert gas
  • Product Name
    1. AEEA-AEEA;
    2. 17-amino-10-oxo-3,6,12,15-tetraoxa-9-azaheptadecan-1-oic acid;
    3. 8-Amino-3,6-dioxaoctanoic acid dimer;
    4. 2-[2-[2-[[2-[2-(2-aminoethoxy)ethoxy]acetyl]amino]ethoxy]ethoxy]acetic acid;
    5. 17-Amino-10-oxo-3,6,12,15-tetraoxa-9-azaheptadecanoic acid
  • Monthly Production Capacity 300 kg/month
  • Applications Side chain building block for peptide synthesis, including Semaglutide, Tirzepatide
Amino Acids & Derivatives for Peptide Synthesis
Amino Acids & Derivatives for Peptide Synthesis
Amino Acids & Derivatives for Peptide Synthesis
  • Related Amino Acids
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Product Name
CAS No.
  • AEEA-AEEA 1143516-05-5
  • AEEA 134978-97-5
  • Fmoc-AEEA-OH 166108-71-0
  • Fmoc-AEEA-AEEA 560088-89-3
  • Boc-AEEA-AEEA 1069067-08-8
Product Name
CAS No.
  • 18-(tert-Butoxy)-18-oxooctadecanoic acid 843666-40-0
  • 20-(tert-Butoxy)-20-oxoicosanoic acid 683239-16-9
  • H-Glu-OtBu 45120-30-7
  • Fmoc-Lys-OH 105047-45-8
Fmoc-L-Lys[Oct-(otBu)-γ-Glu-(otBu)-AEEA-AEEA]-OH
Fmoc-L-Lys[Oct-(otBu)-γ-Glu-(otBu)-AEEA-AEEA]-OH CAS No.: 1662688-20-1
Ste-γ-Glu-AEEA-AEEA-OSU
Ste-γ-Glu-AEEA-AEEA-OSU CAS No.: 1169630-40-3
tBuO-C₁₈-γ-Glu(AEEA-AEEA-OSu)-OtBu
tBuO-C₁₈-γ-Glu(AEEA-AEEA-OSu)-OtBu CAS No.: 166108-71-0
tBuO-Ste-γ-Glu(AEEA-AEEA-OH)-OtBu
tBuO-Ste-γ-Glu(AEEA-AEEA-OH)-OtBu CAS No.: 1118767-16-0
Boc-L-His(Trt)-Aib-OH
Boc-L-His(Trt)-Aib-OH CAS No.: 2061897-68-3
Fmoc-His(Trt)-Aib-OH
Fmoc-His(Trt)-Aib-OH CAS No.: 1446013-13-3
Boc-His(Trt)-Aib-Glu(OtBu)-Gly-OH
Boc-His(Trt)-Aib-Glu(OtBu)-Gly-OH CAS No.: 1890228-73-5
Fmoc-His-Aib-OH TFA
Fmoc-His-Aib-OH TFA CAS No.: 1446013-08-6
Fmoc-Glu(OtBu)-Gly-OH
Fmoc-Glu(OtBu)-Gly-OH CAS No.: 866044-63-5
Fmoc-His-Aib-OH
Fmoc-His-Aib-OH CAS No.: 1446013-07-5
Fmoc-Gly-Arg(Pbf)-OH
Fmoc-Gly-Arg(Pbf)-OH CAS No.: 1048377-78-1
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  • Sherry Wu
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What are some medical applications of peptide-based drugs?

Peptides are used in treating viral infections such as hepatitis, HIV, and SARS. Some can target cancer cells by binding to specific tumor markers or mimicking signaling molecules. Others are derived from natural sources to address cardiovascular conditions, offering a wide range of therapeutic potential.

How do researchers select amino acids when designing peptides?

Longer peptides tend to be more difficult to purify and synthesize due to lower yield and stability. In these cases, auxiliary amino acids may be added at the ends to improve solubility and handling. For shorter peptides, typically under five residues, adding hydrophobic amino acids can enhance structural integrity and functionality.

What role do bioactive peptides play in the food industry?

Bioactive peptides are gaining popularity in functional food and nutrition sectors. These peptides can help regulate physiological processes, support immune health, and delay the onset of chronic diseases. Common sources include dairy proteins, plant extracts, collagen, and marine or animal-derived peptides.

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Amino Acids & Derivatives for Peptide Synthesis
  • Side Chain Raw Material
  • Semaglutide Intermediates
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  • General Protected Amino Acids
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