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  • Fmoc-L-Lys[Oct-(otBu)-γ-Glu-(otBu)-AEEA-AEEA]-OH
Fmoc-L-Lys[Oct-(otBu)-γ-Glu-(otBu)-AEEA-AEEA]-OH

Amino Acids & Derivatives for Peptide Synthesis

Fmoc-L-Lys[Oct-(otBu)-γ-Glu-(otBu)-AEEA-AEEA]-OH

Used in the synthesis of therapeutic peptide Semaglutide

Designed for Semaglutide synthesis, Fmoc-L-Lys[Oct-(otBu)-γ-Glu-(otBu)-AEEA-AEEA]-OH (CAS No. 1662688-20-1, molecular formula C₆₄H₁₀₁N₅O₁₆) is a highly structured white solid intermediate. It features a combination of Fmoc protection, γ-glutamic acid, AEEA spacers, and octanoyl modifications, ideal for introducing complex side chains with improved solubility and controlled reactivity. This type of Semaglutide intermediste is available in 25 kg fiber drums and requires storage at –20 °C in dry conditions to ensure long-term stability.

  • CAS No.: 1662688-20-1
  • Molecular Formula: C₆₄H₁₀₁N₅O₁₆
  • Purity: 99% min
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  • Product Name
    1. Fmoc-L-Lys[Oct-(otBu)-Glu-(otBu)-AEEA-AEEA]-OH;
    2. (3S,30S)-3-Carboxy-30-[(1,1-dimethylethoxy)carbonyl]-9,18,27,32-tetraoxo-49-(1,1-dimethylethyl);
    3. 1-(9H-fluoren-9-ylmethyl)-11,14,20,23-tetraoxa-2,8,17,26,31-pentaazanonatetracontanedioic acid ester;
    4. (23S,50S)-50-((((9H-fluoren-9-yl)methoxy)carbonyl)amino)-23-(tert-butoxycarbonyl)-2,2-dimethyl-4,21,26,35,44-pentaoxo-3,30,33,39,42-pentaoxa-22,27,36,45-tetraazahenpentacontan-51-oic acid;
    5. (2S)-2-(9H-fluoren-9-ylmethoxycarbonylamino)-6-[[2-[2-[2-[[2-[2-[2-[[(4S)-5-[(2-methylpropan-2-yl)oxy]-4-[[18-[(2-methylpropan-2-yl)oxy]-18-oxooctadecanoyl]amino]-5-oxopentanoyl]amino]ethoxy]ethoxy]acetyl]amino]ethoxy]ethoxy]acetyl]amino]hexanoic acid;
    6. (2S)-6-[2-(2-{2-[2-(2-{2-[(4S)-5-(tert-butoxy)-4-[18-(tert-butoxy)-18-oxooctadecanamido]-5-oxopentanamido]ethoxy}ethoxy)acetamido]ethoxy}ethoxy)acetamido]-2-({[(9H-fluoren-9-yl)methoxy]carbonyl}amino)hexanoic acid
  • Appearance White solid
  • Molecular Weight1196.5 g/mol
  • Density N/A
  • Boiling Point N/A
  • Melting Point N/A
  • Flash Point N/A
  • Packaging 25 kg/fibre drum
  • Storage Conditions –20 °C, dry environment
  • Production capacity 500 kg/month
  • Applications Used as an intermediate in the multi-step synthesis of Semaglutide
Amino Acids & Derivatives for Cell Culture
Amino Acids & Derivatives for Cell Culture
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Product Name
CAS No.
  • Fmoc-L-Lys[Oct-(otBu)-γ-Glu-(otBu)-AEEA-AEEA]-OH 1662688-20-1
  • Ste-γ-Glu-AEEA-AEEA-OSU 1169630-40-3
  • tBuO-C₁₈-γ-Glu(AEEA-AEEA-OSu)-OtBu 1118767-15-9
  • tBuO-Ste-γ-Glu(AEEA-AEEA-OH)-OtBu 1118767-16-0
  • Boc-L-His(Trt)-Aib-OH 2061897-68-3
  • Fmoc-His(Trt)-Aib-OH 1446013-13-3
Product Name
CAS No.
  • Boc-His(Trt)-Aib-Glu(OtBu)-Gly-OH 1890228-73-5
  • Fmoc-His-Aib-OH TFA 1446013-08-6
  • Fmoc-Glu(OtBu)-Gly-OH 866044-63-5
  • Fmoc-His-Aib-OH 1446013-07-5
  • Fmoc-Gly-Arg(Pbf)-OH 1048377-78-1
Fmoc-L-Lys[C₂₀-OtBu-γ-Glu(OtBu)-AEEA-AEEA]-OH
Fmoc-L-Lys[C₂₀-OtBu-γ-Glu(OtBu)-AEEA-AEEA]-OH CAS No.: 2915356-76-0
tBuO-C₂₀-γ-Glu(AEEA-AEEA-OSu)-OtBu
tBuO-C₂₀-γ-Glu(AEEA-AEEA-OSu)-OtBu CAS No.: 1118767-17-1
C₂₀-OtBu-γ-Glu(OtBu)-AEEA-AEEA-OH
C₂₀-OtBu-γ-Glu(OtBu)-AEEA-AEEA-OH CAS No.: 1188328-37-1
C₂₀-γ-Glu(AEEA-AEEA-OSu)-OH
C₂₀-γ-Glu(AEEA-AEEA-OSu)-OH CAS No.: 1188328-38-2
Boc-Tyr(tBu)-Aib-OH
Boc-Tyr(tBu)-Aib-OH CAS No.: 2639221-78-4
Fmoc-Ile-Aib-OH
Fmoc-Ile-Aib-OH CAS No.: 2171139-20-9
Boc-Tyr(tBu)-Aib-Glu(OtBu)-Gly-OH
Boc-Tyr(tBu)-Aib-Glu(OtBu)-Gly-OH CAS No.: 2682040-93-1
Fmoc-Ala-Pro-OH
Fmoc-Ala-Pro-OH CAS No.: 186023-44-9
Fmoc-Ser(tBu)-Gly-OH
Fmoc-Ser(tBu)-Gly-OH CAS No.: 81672-17-5
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What are some medical applications of peptide-based drugs?

Peptides are used in treating viral infections such as hepatitis, HIV, and SARS. Some can target cancer cells by binding to specific tumor markers or mimicking signaling molecules. Others are derived from natural sources to address cardiovascular conditions, offering a wide range of therapeutic potential.

How do researchers select amino acids when designing peptides?

Longer peptides tend to be more difficult to purify and synthesize due to lower yield and stability. In these cases, auxiliary amino acids may be added at the ends to improve solubility and handling. For shorter peptides, typically under five residues, adding hydrophobic amino acids can enhance structural integrity and functionality.

What role do bioactive peptides play in the food industry?

Bioactive peptides are gaining popularity in functional food and nutrition sectors. These peptides can help regulate physiological processes, support immune health, and delay the onset of chronic diseases. Common sources include dairy proteins, plant extracts, collagen, and marine or animal-derived peptides.

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