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  • Fmoc-His-Aib-OH TFA
Fmoc-His-Aib-OH TFA

Amino Acids & Derivatives for Peptide Synthesis

Fmoc-His-Aib-OH TFA

Used in the synthesis of therapeutic peptide Semaglutide

Formulated to be used in Semaglutide synthesis, Fmoc-His-Aib-OH TFA (CAS No. 1446013-08-6, molecular formula C27H27F3N4O7) is a white to off-white intermediate solid that includes Fmoc-protected histidine and Aib (α-aminoisobutyric acid), delivered as a TFA salt. With a molecular weight of 576.5 g/mol and a purity of at least 99%, this compound is supplied in 25 kg fibre drums. It must be stored in sealed packaging under refrigeration to maintain stability and reactivity.

  • CAS No.: 1446013-08-6
  • Molecular Formula: C₂₇H₂₇F₃N₄O₇
  • Purity: 99% min
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  • Appearance White or off-white solid
  • Molecular Weight 576.5 g/mol
  • Density N/A
  • Boiling Point N/A
  • Melting Point N/A
  • Flash Point N/A
  • Packaging 25 kg/fibre drum
  • Storage Conditions Store refrigerated (2–8 °C) in a sealed, dry container
  • Production Volume per Batch 200 kg
  • Production Cycle 8 days
  • Product Name
    1. Fmoc-His-Aib-OH TFA
  • Production capacity 1000 kg/month
  • Applications Intermediate for Semaglutide peptide synthesis
Amino Acids & Derivatives for Cell Culture
Amino Acids & Derivatives for Cell Culture
Amino Acids & Derivatives for Cell Culture
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Product Name
CAS No.
  • Fmoc-L-Lys[Oct-(otBu)-γ-Glu-(otBu)-AEEA-AEEA]-OH 1662688-20-1
  • Ste-γ-Glu-AEEA-AEEA-OSU 1169630-40-3
  • tBuO-C₁₈-γ-Glu(AEEA-AEEA-OSu)-OtBu 1118767-15-9
  • tBuO-Ste-γ-Glu(AEEA-AEEA-OH)-OtBu 1118767-16-0
  • Boc-L-His(Trt)-Aib-OH 2061897-68-3
  • Fmoc-His(Trt)-Aib-OH 1446013-13-3
Product Name
CAS No.
  • Boc-His(Trt)-Aib-Glu(OtBu)-Gly-OH 1890228-73-5
  • Fmoc-His-Aib-OH TFA 1446013-08-6
  • Fmoc-Glu(OtBu)-Gly-OH 866044-63-5
  • Fmoc-His-Aib-OH 1446013-07-5
  • Fmoc-Gly-Arg(Pbf)-OH 1048377-78-1
Fmoc-Ala-Pro-OH
Fmoc-Ala-Pro-OH CAS No.: 186023-44-9
Fmoc-Ser(tBu)-Gly-OH
Fmoc-Ser(tBu)-Gly-OH CAS No.: 81672-17-5
Fmoc-L-Lys[C₂₀-OtBu-γ-Glu(OtBu)-AEEA-AEEA]-OH
Fmoc-L-Lys[C₂₀-OtBu-γ-Glu(OtBu)-AEEA-AEEA]-OH CAS No.: 2915356-76-0
tBuO-C₂₀-γ-Glu(AEEA-AEEA-OSu)-OtBu
tBuO-C₂₀-γ-Glu(AEEA-AEEA-OSu)-OtBu CAS No.: 1118767-17-1
C₂₀-OtBu-γ-Glu(OtBu)-AEEA-AEEA-OH
C₂₀-OtBu-γ-Glu(OtBu)-AEEA-AEEA-OH CAS No.: 1188328-37-1
C₂₀-γ-Glu(AEEA-AEEA-OSu)-OH
C₂₀-γ-Glu(AEEA-AEEA-OSu)-OH CAS No.: 1188328-38-2
Boc-Tyr(tBu)-Aib-OH
Boc-Tyr(tBu)-Aib-OH CAS No.: 2639221-78-4
Fmoc-Ile-Aib-OH
Fmoc-Ile-Aib-OH CAS No.: 2171139-20-9
Boc-Tyr(tBu)-Aib-Glu(OtBu)-Gly-OH
Boc-Tyr(tBu)-Aib-Glu(OtBu)-Gly-OH CAS No.: 2682040-93-1
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What are some medical applications of peptide-based drugs?

Peptides are used in treating viral infections such as hepatitis, HIV, and SARS. Some can target cancer cells by binding to specific tumor markers or mimicking signaling molecules. Others are derived from natural sources to address cardiovascular conditions, offering a wide range of therapeutic potential.

How do researchers select amino acids when designing peptides?

Longer peptides tend to be more difficult to purify and synthesize due to lower yield and stability. In these cases, auxiliary amino acids may be added at the ends to improve solubility and handling. For shorter peptides, typically under five residues, adding hydrophobic amino acids can enhance structural integrity and functionality.

What role do bioactive peptides play in the food industry?

Bioactive peptides are gaining popularity in functional food and nutrition sectors. These peptides can help regulate physiological processes, support immune health, and delay the onset of chronic diseases. Common sources include dairy proteins, plant extracts, collagen, and marine or animal-derived peptides.

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