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  • Ste-γ-Glu-AEEA-AEEA-OSU
Ste-γ-Glu-AEEA-AEEA-OSU

Amino Acids & Derivatives for Peptide Synthesis

Ste-γ-Glu-AEEA-AEEA-OSU

Used in the synthesis of therapeutic peptide Semaglutide

As part of the peptide chain construction in Semaglutide synthesis, Ste-γ-Glu-AEEA-AEEA-OSU (CAS No. 1169630-40-3, C₃₉H₆₆N₄O₁₅) acts as an activated intermediate designed for efficient coupling. It combines a stearoylated γ-glutamic acid backbone with two AEEA spacers and an N-hydroxysuccinimide (OSu) ester, making it well-suited for integration into long-chain peptides. This off-white powder offers a purity of ≥98% and a molecular weight of 831.0 g/mol. It’s supplied in 25 kg fiber drums and should be kept sealed at –20 °C ±5 °C to preserve its reactivity and overall stability.

  • CAS No.: 1169630-40-3
  • Molecular Formula: C₃₉H₆₆N₄O₁₅
  • Purity: 98% min
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  • Appearance White to off-white powder
  • Molecular Weight 831.0 g/mol
  • Density 1.23 ± 0.1 g/cm³ (predicted)
  • Boiling Point N/A
  • Melting Point N/A
  • Flash Point N/A
  • Packaging 25 kg/fibre drum
  • Storage Conditions Store sealed at –20 °C ±5 °C
  • Batch Capacity 100 kg
  • Production Cycle 15 days
  • Product Name
    1. Ste-γ-Glu-AEEA-AEEA-OSU;
    2. 18-[[(1s)-1-carboxy-4-[2-[2-[2-[2-[2,5-dioxopyrrolidin-1-yl)oxy]-2-oxoethoxy]ethoxy]ethylamino]-2-oxo-ethoxy]ethoxy]ethylamino]-4-oxo-butyl]amino]-18-oxo-octadecanoic acid
  • Production capacity 500 kg/month
  • Applications Intermediate used in the synthesis of Semaglutide
Amino Acids & Derivatives for Cell Culture
Amino Acids & Derivatives for Cell Culture
Amino Acids & Derivatives for Cell Culture
  • Related Amino Acids
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Product Name
CAS No.
  • Fmoc-L-Lys[Oct-(otBu)-γ-Glu-(otBu)-AEEA-AEEA]-OH 1662688-20-1
  • Ste-γ-Glu-AEEA-AEEA-OSU 1169630-40-3
  • tBuO-C₁₈-γ-Glu(AEEA-AEEA-OSu)-OtBu 1118767-15-9
  • tBuO-Ste-γ-Glu(AEEA-AEEA-OH)-OtBu 1118767-16-0
  • Boc-L-His(Trt)-Aib-OH 2061897-68-3
  • Fmoc-His(Trt)-Aib-OH 1446013-13-3
Product Name
CAS No.
  • Boc-His(Trt)-Aib-Glu(OtBu)-Gly-OH 1890228-73-5
  • Fmoc-His-Aib-OH TFA 1446013-08-6
  • Fmoc-Glu(OtBu)-Gly-OH 866044-63-5
  • Fmoc-His-Aib-OH 1446013-07-5
  • Fmoc-Gly-Arg(Pbf)-OH 1048377-78-1
C₂₀-OtBu-γ-Glu(OtBu)-AEEA-AEEA-OH
C₂₀-OtBu-γ-Glu(OtBu)-AEEA-AEEA-OH CAS No.: 1188328-37-1
C₂₀-γ-Glu(AEEA-AEEA-OSu)-OH
C₂₀-γ-Glu(AEEA-AEEA-OSu)-OH CAS No.: 1188328-38-2
Boc-Tyr(tBu)-Aib-OH
Boc-Tyr(tBu)-Aib-OH CAS No.: 2639221-78-4
Fmoc-Ile-Aib-OH
Fmoc-Ile-Aib-OH CAS No.: 2171139-20-9
Boc-Tyr(tBu)-Aib-Glu(OtBu)-Gly-OH
Boc-Tyr(tBu)-Aib-Glu(OtBu)-Gly-OH CAS No.: 2682040-93-1
Fmoc-Ala-Pro-OH
Fmoc-Ala-Pro-OH CAS No.: 186023-44-9
Fmoc-Ser(tBu)-Gly-OH
Fmoc-Ser(tBu)-Gly-OH CAS No.: 81672-17-5
Fmoc-L-Lys[C₂₀-OtBu-γ-Glu(OtBu)-AEEA-AEEA]-OH
Fmoc-L-Lys[C₂₀-OtBu-γ-Glu(OtBu)-AEEA-AEEA]-OH CAS No.: 2915356-76-0
tBuO-C₂₀-γ-Glu(AEEA-AEEA-OSu)-OtBu
tBuO-C₂₀-γ-Glu(AEEA-AEEA-OSu)-OtBu CAS No.: 1118767-17-1
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  • Sherry Wu
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What are some medical applications of peptide-based drugs?

Peptides are used in treating viral infections such as hepatitis, HIV, and SARS. Some can target cancer cells by binding to specific tumor markers or mimicking signaling molecules. Others are derived from natural sources to address cardiovascular conditions, offering a wide range of therapeutic potential.

How do researchers select amino acids when designing peptides?

Longer peptides tend to be more difficult to purify and synthesize due to lower yield and stability. In these cases, auxiliary amino acids may be added at the ends to improve solubility and handling. For shorter peptides, typically under five residues, adding hydrophobic amino acids can enhance structural integrity and functionality.

What role do bioactive peptides play in the food industry?

Bioactive peptides are gaining popularity in functional food and nutrition sectors. These peptides can help regulate physiological processes, support immune health, and delay the onset of chronic diseases. Common sources include dairy proteins, plant extracts, collagen, and marine or animal-derived peptides.

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info@cd-bsx.com
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