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Glycyl-L-tyrosine dihydrate

Amino Acids & Derivatives for Cell Culture

Glycyl-L-tyrosine dihydrate

Used in cell culture media for supporting cell growth and proliferation

Glycyl-L-tyrosine dihydrate (CAS No. 39630-46-1) is a hydrated dipeptide composed of glycine and tyrosine, provided as a white to off-white solid with 99% min purity and a molecular weight of 274.27 g/mol. It is used in cell culture media to deliver a reliable source of tyrosine in a form that offers better solubility and handling stability than the free amino acid. This compound is suitable for media formulations requiring precise amino acid composition, such as those used in serum-free or defined systems. To maintain its integrity, it must be stored in a sealed container at 2–8 °C. Each unit is supplied in 25 kg fiber drums, with stable production to meet routine formulation and scale-up needs.

  • CAS No.: 39630-46-1
  • Molecular Formula: C₁₁H₁₈N₂O₆
  • Purity: 99% min
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  • Appearance White to white-like solid
  • Molecular Weight 274.27 g/mol
  • Density N/A
  • Boiling Point N/A
  • Melting Point N/A
  • Flash Point 387.5 °C
  • Packaging 25 kg per fibre drum
  • Customs Code 2924296000
  • Storage Conditions Store at 2–8 °C in a sealed container
  • Product Name
    1. Glycyl tyrosine;
    2. (2S)-2-[(2-aminoacetyl)amino]-3-(4-hydroxyphenyl)propanoic acid, dihydrate
  • Production capacity 3 tons/month
  • Applications Cell culture media component
Amino Acids & Derivatives for Cell Culture
Amino Acids & Derivatives for Cell Culture
Amino Acids & Derivatives for Cell Culture
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Product Name
CAS No.
  • L-Tyrosine 60-18-4
  • L-Tyrosine disodium salt 122666-87-9
  • N-Acetyl-L-tryptophan 1218-34-4
  • N-Acetyl-DL-tryptophan 87-32-1
  • L-Cystine dihydrochloride 30925-07-6
  • L-Cystine disodium salt monohydrate 199329-53-8
  • L-Cysteine S-sulfate sodium 150465-29-5
  • Phospho-L-tyrosine disodium salt 1610350-91-8
  • L-Aspartic acid monosodium salt monohydrate 323194-76-9
  • Glycylglycine 556-50-3
  • Triglycine 139-13-9
Product Name
CAS No.
  • Ala-Ala-Ala 5874-90-8
  • L-Alanyl-L-cystine 115888-13-6
  • L-Alanyl-L-tyrosine 3061-88-9
  • Glycyl-L-tyrosine 658-79-7
  • Glycyl-L-tyrosine dihydrate 39630-46-1
  • L-Alanyl-L-Glutamine 39537-23-0
  • L-Carnosine 305-84-0
  • Glycyl-L-glutamine monohydrate 13115-71-4
  • N,N'-Di-L-lysyl-L-cystine dihydrochloride 2920735-07-3
  • α-Ketoglutaric acid 328-50-7
Fmoc-L-Lys[C₂₀-OtBu-γ-Glu(OtBu)-AEEA]-OH
Fmoc-L-Lys[C₂₀-OtBu-γ-Glu(OtBu)-AEEA]-OH CAS No.: 2612237-97-3
Fmoc-Lys[γ-Glu(OtBu)-C₁₈-OtBu)]-OH
Fmoc-Lys[γ-Glu(OtBu)-C₁₈-OtBu)]-OH CAS No.: 1931109-48-6
Boc-L-His(Trt)-1-Aminocyclobutanecarboxylic acid
Boc-L-His(Trt)-1-Aminocyclobutanecarboxylic acid CAS No.: N/A
L-Glutamic acid α-tert-butyl ester
L-Glutamic acid α-tert-butyl ester CAS No.: 45120-30-7
Boc-His(Trt)-Aib-GIn(Trt)-Gly-OH
Boc-His(Trt)-Aib-GIn(Trt)-Gly-OH CAS No.: N/A
Boc-His(Trt)-Ala-Glu(OtBu)-Gly-OH
Boc-His(Trt)-Ala-Glu(OtBu)-Gly-OH CAS No.: 1418291-58-3
Fmoc-Thr(tBu)-Phe-OH
Fmoc-Thr(tBu)-Phe-OH CAS No.: 1962160-86-6
Fmoc-Gly-Ser[PSI(Me,Me)pro]-OH
Fmoc-Gly-Ser[PSI(Me,Me)pro]-OH CAS No.: 1095952-22-9
Fmoc-Tyr(tBu)-Ser(MeMe)pro-OH
Fmoc-Tyr(tBu)-Ser(MeMe)pro-OH CAS No.: 878797-09-2
Fmoc-N(HMB)-Gly-OH
Fmoc-N(HMB)-Gly-OH CAS No.: 148515-78-0
Fmoc-Ser(tBu)-Ser[Psi(Me,Me)Pro]-OH
Fmoc-Ser(tBu)-Ser[Psi(Me,Me)Pro]-OH CAS No.: 1000164-43-1
H-Gly-Pro-Hyp-OH
H-Gly-Pro-Hyp-OH CAS No.: 2239-67-0
Boc-His(Trt)-Ala-OH
Boc-His(Trt)-Ala-OH CAS No.: 1454254-70-6
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  • Sherry Wu
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What roles do amino acids play in cell culture media?

Amino acids are essential building blocks for protein synthesis and act as key intermediates in numerous metabolic pathways. In cell culture, they are vital for promoting growth, supporting cell division, and maintaining cellular homeostasis. Proper amino acid supplementation ensures high viability, accelerates proliferation, and boosts experimental reproducibility.

How is glycylglycine (a dipeptide) used in the pharmaceutical and biotech industries?

Glycylglycine is commonly used to:

  • Enhance the uptake of amino acids in cell culture environments
  • Support the formulation of specialized medical and nutritional products
  • Serve as a substrate in enzymatic assays for dipeptidase activity
  • Act as an absorption enhancer in oral drug delivery systems to improve bioavailability

Why is S-sulfo-L-cysteine sodium salt added to mammalian cell culture media?

This amino acid derivative is chosen for its excellent solubility at neutral pH, making it suitable for feed strategies during high-density cultivation. It minimizes localized pH shifts and prevents thermal stress during buffer adjustments. Its use improves media preparation efficiency and supports higher protein expression in recombinant systems.

Which amino acids are beneficial for liver support?

  • Branched-chain amino acids (BCAAs) aid in liver regeneration and help manage symptoms of hepatic encephalopathy.
  • Glutamine contributes to gut barrier function and supports amino acid metabolism.
  • Arginine assists in detoxifying ammonia through the urea cycle.
    If you're looking for a formulation to improve liver function, feel free to reach out to our specialists for tailored guidance.

How can cell growth rate and survival be improved in culture?

Supplementing media with L-Tyrosine can help reduce oxidative stress and support healthier cell growth. It is especially important in serum-free or chemically defined media and is widely used in monoclonal antibody production, particularly with CHO and hybridoma cells.

What impact do amino acids have on mammalian cell behavior?

Beyond protein synthesis, amino acids are involved in signal transduction, membrane integrity, and cellular defense. Their metabolic fate influences energy balance, redox status, and the synthesis of critical cellular components, directly affecting cell health, productivity, and adaptability.

What is the role of L-Tyrosine in CHO cell culture?

L-Tyrosine plays a key role in the synthesis of structural proteins and enzymes. In CHO cell media, it enhances biomass production and supports robust cell growth, making it a critical supplement in biopharmaceutical manufacturing where consistent yields are required.

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Cosmetic Raw Materials & Intermediates Cosmetic Raw Materials & Intermediates
Amino Acids & Derivatives for Cell Culture
  • L-Tyrosine
  • L-Tyrosine disodium salt
  • N-Acetyl-L-tryptophan
  • N-Acetyl-DL-tryptophan
  • L-Cystine dihydrochloride
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Amino Acids & Derivatives for Peptide Synthesis
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Sherry Wu
info@cd-bsx.com
+86-28-88531548
+86-13730848292