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Phospho-L-tyrosine disodium salt

Amino Acids & Derivatives for Cell Culture

Phospho-L-tyrosine disodium salt

Used in cell culture media for supporting cell growth and proliferation

Used in cell culture formulations that require precise control over nutrient composition, Phospho-L-tyrosine disodium salt (CAS No. 1610350-91-8) offers a stable, soluble form of tyrosine suitable for serum-free and chemically defined systems. This amino acid derivative appears as a crystalline solid, with a molecular weight of 305.13 g/mol, density of 1.71 g/cm³ at 20 °C, and purity 99% min. Supplied in 25 kg fibre drums, it is stored between 2–8 °C to preserve quality. With a monthly output of 1 ton, it supports consistent application in suspension cultures and high-performance bioproduction environments.

  • CAS No.: 1610350-91-8
  • Molecular Formula: C₉H₁₀NNa₂O₆P
  • Purity: 99% min
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  • Appearance Solid crystallization
  • Molecular Weight 305.13 g/mol
  • Density 1.71 g/cm³ at 20 °C
  • Boiling Point N/A
  • Melting Point N/A
  • Flash Point N/A
  • Packaging 25 kg per fibre drum
  • Storage Conditions 2–8 °C
  • Product Name
    1. Phospho-L-tyrosine disodium salt;
    2. (S)-2-amino-3-(4-((hydroxyoxidophosphoryl)oxy)phenyl)propanoate
  • Production capacity 1 tons/month
  • Applications Raw material for cell culture media
Amino Acids & Derivatives for Cell Culture
Amino Acids & Derivatives for Cell Culture
Amino Acids & Derivatives for Cell Culture
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Boc-His(Trt)-Aib-Glu(OtBu)-Gly-OH CAS No.: 1890228-73-5
Fmoc-His-Aib-OH TFA
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  • Sherry Wu
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What is the role of Phospho-L-tyrosine disodium salt in serum-free media?

Phospho-L-tyrosine disodium salt provides a stable, water-soluble form of tyrosine that enhances solubility and formulation consistency in serum-free or chemically defined media. It helps maintain balanced nutrient delivery in suspension cultures and supports reproducibility in large-scale applications.

What roles do amino acids play in cell culture media?

Amino acids are essential building blocks for protein synthesis and act as key intermediates in numerous metabolic pathways. In cell culture, they are vital for promoting growth, supporting cell division, and maintaining cellular homeostasis. Proper amino acid supplementation ensures high viability, accelerates proliferation, and boosts experimental reproducibility.

How is glycylglycine (a dipeptide) used in the pharmaceutical and biotech industries?

Glycylglycine is commonly used to:

  • Enhance the uptake of amino acids in cell culture environments
  • Support the formulation of specialized medical and nutritional products
  • Serve as a substrate in enzymatic assays for dipeptidase activity
  • Act as an absorption enhancer in oral drug delivery systems to improve bioavailability

Why is S-sulfo-L-cysteine sodium salt added to mammalian cell culture media?

This amino acid derivative is chosen for its excellent solubility at neutral pH, making it suitable for feed strategies during high-density cultivation. It minimizes localized pH shifts and prevents thermal stress during buffer adjustments. Its use improves media preparation efficiency and supports higher protein expression in recombinant systems.

Which amino acids are beneficial for liver support?

  • Branched-chain amino acids (BCAAs) aid in liver regeneration and help manage symptoms of hepatic encephalopathy.
  • Glutamine contributes to gut barrier function and supports amino acid metabolism.
  • Arginine assists in detoxifying ammonia through the urea cycle.
    If you're looking for a formulation to improve liver function, feel free to reach out to our specialists for tailored guidance.

How can cell growth rate and survival be improved in culture?

Supplementing media with L-Tyrosine can help reduce oxidative stress and support healthier cell growth. It is especially important in serum-free or chemically defined media and is widely used in monoclonal antibody production, particularly with CHO and hybridoma cells.

What impact do amino acids have on mammalian cell behavior?

Beyond protein synthesis, amino acids are involved in signal transduction, membrane integrity, and cellular defense. Their metabolic fate influences energy balance, redox status, and the synthesis of critical cellular components, directly affecting cell health, productivity, and adaptability.

What is the role of L-Tyrosine in CHO cell culture?

L-Tyrosine plays a key role in the synthesis of structural proteins and enzymes. In CHO cell media, it enhances biomass production and supports robust cell growth, making it a critical supplement in biopharmaceutical manufacturing where consistent yields are required.

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Amino Acids & Derivatives for Cell Culture
  • L-Tyrosine
  • L-Tyrosine disodium salt
  • N-Acetyl-L-tryptophan
  • N-Acetyl-DL-tryptophan
  • L-Cystine dihydrochloride
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Sherry Wu
info@cd-bsx.com
+86-28-88531548
+86-13730848292