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Glycyl-L-tyrosine

Amino Acids & Derivatives for Cell Culture

Glycyl-L-tyrosine

Used in cell culture media for supporting cell growth and proliferation

Glycyl-L-tyrosine (CAS No. 658-79-7) is a white to light yellow dipeptide solid composed of glycine and tyrosine. It has a molecular weight of 238.24 g/mol and 99% min purity. This compound is commonly used in cell culture media and as a raw material in pharmaceutical applications, particularly in systems aimed at supporting cell growth and protein production. Its structure combines two essential amino acids involved in metabolic and biosynthetic processes, making it a useful supplement for high-density cell culture. To maintain product integrity, it must be stored sealed and dry at temperatures below –20 °C.

  • CAS No.: 658-79-7
  • Molecular Formula: C₁₁H₁₄N₂O₄
  • Purity: 99% min
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  • Appearance White to light yellow solid
  • Molecular Weight 238.24 g/mol
  • Density 1.4 ± 0.1 g/cm³
  • Boiling Point 568.4 ± 50.0 °C at 760 mmHg
  • Melting Point 278–285 °C (decomposition)
  • Flash Point 297.6 ± 30.1 °C
  • Packaging 25 kg per fibre drum
  • Customs Code 29242990
  • Storage Conditions Store sealed and dry, in a freezer below –20 °C
  • Product Name
    1. L-Alanyl-L-Tyrosine;
    2. H-Ala-Tyr-OH;
    3. (2S)-2-[[(2S)-2-aminopropanoyl]amino]-3-(4-hydroxyphenyl)propanoic acid
  • Production capacity 3 tons/month
  • Applications Cell culture media ingredient, API intermediate
Amino Acids & Derivatives for Cell Culture
Amino Acids & Derivatives for Cell Culture
Amino Acids & Derivatives for Cell Culture
  • Related Amino Acids
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Product Name
CAS No.
  • L-Tyrosine 60-18-4
  • L-Tyrosine disodium salt 122666-87-9
  • N-Acetyl-L-tryptophan 1218-34-4
  • N-Acetyl-DL-tryptophan 87-32-1
  • L-Cystine dihydrochloride 30925-07-6
  • L-Cystine disodium salt monohydrate 199329-53-8
  • L-Cysteine S-sulfate sodium 150465-29-5
  • Phospho-L-tyrosine disodium salt 1610350-91-8
  • L-Aspartic acid monosodium salt monohydrate 323194-76-9
  • Glycylglycine 556-50-3
  • Triglycine 139-13-9
Product Name
CAS No.
  • Ala-Ala-Ala 5874-90-8
  • L-Alanyl-L-cystine 115888-13-6
  • L-Alanyl-L-tyrosine 3061-88-9
  • Glycyl-L-tyrosine 658-79-7
  • Glycyl-L-tyrosine dihydrate 39630-46-1
  • L-Alanyl-L-Glutamine 39537-23-0
  • L-Carnosine 305-84-0
  • Glycyl-L-glutamine monohydrate 13115-71-4
  • N,N'-Di-L-lysyl-L-cystine dihydrochloride 2920735-07-3
  • α-Ketoglutaric acid 328-50-7
tBuO-C₂₀-γ-Glu(AEEA-AEEA-OSu)-OtBu
tBuO-C₂₀-γ-Glu(AEEA-AEEA-OSu)-OtBu CAS No.: 1118767-17-1
C₂₀-OtBu-γ-Glu(OtBu)-AEEA-AEEA-OH
C₂₀-OtBu-γ-Glu(OtBu)-AEEA-AEEA-OH CAS No.: 1188328-37-1
C₂₀-γ-Glu(AEEA-AEEA-OSu)-OH
C₂₀-γ-Glu(AEEA-AEEA-OSu)-OH CAS No.: 1188328-38-2
Boc-Tyr(tBu)-Aib-OH
Boc-Tyr(tBu)-Aib-OH CAS No.: 2639221-78-4
Fmoc-Ile-Aib-OH
Fmoc-Ile-Aib-OH CAS No.: 2171139-20-9
Boc-Tyr(tBu)-Aib-Glu(OtBu)-Gly-OH
Boc-Tyr(tBu)-Aib-Glu(OtBu)-Gly-OH CAS No.: 2682040-93-1
Fmoc-Ala-Pro-OH
Fmoc-Ala-Pro-OH CAS No.: 186023-44-9
Fmoc-Ser(tBu)-Gly-OH
Fmoc-Ser(tBu)-Gly-OH CAS No.: 81672-17-5
Fmoc-L-Lys[C₂₀-OtBu-γ-Glu(OtBu)-AEEA-AEEA]-OH
Fmoc-L-Lys[C₂₀-OtBu-γ-Glu(OtBu)-AEEA-AEEA]-OH CAS No.: 2915356-76-0
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  • Sherry Wu
  • +86-13730848292

How does Glycyl-L-tyrosine support cell proliferation?

As a dipeptide composed of glycine and tyrosine, Glycyl-L-tyrosine plays an active role in promoting cell growth and division in nutrient-rich media. It supplies essential building blocks for protein synthesis and supports energy metabolism, particularly in high-performance culture systems focused on cell expansion.

What roles do amino acids play in cell culture media?

Amino acids are essential building blocks for protein synthesis and act as key intermediates in numerous metabolic pathways. In cell culture, they are vital for promoting growth, supporting cell division, and maintaining cellular homeostasis. Proper amino acid supplementation ensures high viability, accelerates proliferation, and boosts experimental reproducibility.

How is glycylglycine (a dipeptide) used in the pharmaceutical and biotech industries?

Glycylglycine is commonly used to:

  • Enhance the uptake of amino acids in cell culture environments
  • Support the formulation of specialized medical and nutritional products
  • Serve as a substrate in enzymatic assays for dipeptidase activity
  • Act as an absorption enhancer in oral drug delivery systems to improve bioavailability

Why is S-sulfo-L-cysteine sodium salt added to mammalian cell culture media?

This amino acid derivative is chosen for its excellent solubility at neutral pH, making it suitable for feed strategies during high-density cultivation. It minimizes localized pH shifts and prevents thermal stress during buffer adjustments. Its use improves media preparation efficiency and supports higher protein expression in recombinant systems.

Which amino acids are beneficial for liver support?

  • Branched-chain amino acids (BCAAs) aid in liver regeneration and help manage symptoms of hepatic encephalopathy.
  • Glutamine contributes to gut barrier function and supports amino acid metabolism.
  • Arginine assists in detoxifying ammonia through the urea cycle.
    If you're looking for a formulation to improve liver function, feel free to reach out to our specialists for tailored guidance.

How can cell growth rate and survival be improved in culture?

Supplementing media with L-Tyrosine can help reduce oxidative stress and support healthier cell growth. It is especially important in serum-free or chemically defined media and is widely used in monoclonal antibody production, particularly with CHO and hybridoma cells.

What impact do amino acids have on mammalian cell behavior?

Beyond protein synthesis, amino acids are involved in signal transduction, membrane integrity, and cellular defense. Their metabolic fate influences energy balance, redox status, and the synthesis of critical cellular components, directly affecting cell health, productivity, and adaptability.

What is the role of L-Tyrosine in CHO cell culture?

L-Tyrosine plays a key role in the synthesis of structural proteins and enzymes. In CHO cell media, it enhances biomass production and supports robust cell growth, making it a critical supplement in biopharmaceutical manufacturing where consistent yields are required.

Raw Materials & Intermediates
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Agricultural Raw Materials & Intermediates Agricultural Raw Materials & Intermediates
Cosmetic Raw Materials & Intermediates Cosmetic Raw Materials & Intermediates
Amino Acids & Derivatives for Cell Culture
  • L-Tyrosine
  • L-Tyrosine disodium salt
  • N-Acetyl-L-tryptophan
  • N-Acetyl-DL-tryptophan
  • L-Cystine dihydrochloride
  • View More
Amino Acids & Derivatives for Peptide Synthesis
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  • Semaglutide Intermediates
  • Tirzepatide Intermediates
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  • General Protected Amino Acids
Raw Materials & Intermediates
  • Pharmaceutical Raw Materials & Intermediates
  • Food Additive Raw Materials & Intermediates
  • Agricultural Raw Materials & Intermediates
  • Cosmetic Raw Materials & Intermediates
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Sherry Wu
info@cd-bsx.com
+86-28-88531548
+86-13730848292