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  • L-Alanyl-L-tyrosine
L-Alanyl-L-tyrosine

Amino Acids & Derivatives for Cell Culture

L-Alanyl-L-tyrosine

Used in cell culture media for supporting cell growth and proliferation

As a dipeptide combining alanine and tyrosine, L-Alanyl-L-tyrosine (CAS No. 3061-88-9) is used to support cell growth in environments that demand precise amino acid control. It appears as a white crystalline powder, with a molecular weight of 252.27 g/mol and 99% min purity. This compound has an important role in chemically defined media by delivering tyrosine in a more soluble and stable form than its free amino acid counterpart. It is beneficial for cell culture systems requiring consistency and high-performance protein synthesis. To preserve its quality and stability, L-Alanyl-L-tyrosine should be stored at –20 °C in sealed containers. It is available in 25 kg fibre drums, and production is maintained at up to 3 tons per month to meet both research and manufacturing demands.

  • CAS No.: 3061-88-9
  • Molecular Formula: C₁₂H₁₆N₂O₄
  • Purity: 99% min
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  • Appearance White crystalline powder
  • Molecular Weight 252.27 g/mol
  • Density 1.3 ± 0.1 g/cm³
  • Boiling Point 558.0 ± 50.0 °C at 760 mmHg
  • Melting Point 238–240 °C (decomposition)
  • Flash Point 291.2 ± 30.1 °C
  • Packaging 25 kg per fibre drum
  • Customs Code 2924299090
  • Storage Conditions Store at –20 °C in sealed containers
  • Product Name
    1. L-Alanyl-L-Tyrosine;
    2. H-Ala-Tyr-OH;
    3. (2S)-2-[[(2S)-2-aminopropanoyl]amino]-3-(4-hydroxyphenyl)propanoic acid
  • Production capacity 3 tons/month
  • Applications Cell culture media (chemically defined), API raw material
Amino Acids & Derivatives for Cell Culture
Amino Acids & Derivatives for Cell Culture
Amino Acids & Derivatives for Cell Culture
  • Related Amino Acids
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Product Name
CAS No.
  • L-Tyrosine 60-18-4
  • L-Tyrosine disodium salt 122666-87-9
  • N-Acetyl-L-tryptophan 1218-34-4
  • N-Acetyl-DL-tryptophan 87-32-1
  • L-Cystine dihydrochloride 30925-07-6
  • L-Cystine disodium salt monohydrate 199329-53-8
  • L-Cysteine S-sulfate sodium 150465-29-5
  • Phospho-L-tyrosine disodium salt 1610350-91-8
  • L-Aspartic acid monosodium salt monohydrate 323194-76-9
  • Glycylglycine 556-50-3
  • Triglycine 139-13-9
Product Name
CAS No.
  • Ala-Ala-Ala 5874-90-8
  • L-Alanyl-L-cystine 115888-13-6
  • L-Alanyl-L-tyrosine 3061-88-9
  • Glycyl-L-tyrosine 658-79-7
  • Glycyl-L-tyrosine dihydrate 39630-46-1
  • L-Alanyl-L-Glutamine 39537-23-0
  • L-Carnosine 305-84-0
  • Glycyl-L-glutamine monohydrate 13115-71-4
  • N,N'-Di-L-lysyl-L-cystine dihydrochloride 2920735-07-3
  • α-Ketoglutaric acid 328-50-7
Fmoc-Ser(tBu)-Gly-OH
Fmoc-Ser(tBu)-Gly-OH CAS No.: 81672-17-5
Fmoc-L-Lys[C₂₀-OtBu-γ-Glu(OtBu)-AEEA-AEEA]-OH
Fmoc-L-Lys[C₂₀-OtBu-γ-Glu(OtBu)-AEEA-AEEA]-OH CAS No.: 2915356-76-0
tBuO-C₂₀-γ-Glu(AEEA-AEEA-OSu)-OtBu
tBuO-C₂₀-γ-Glu(AEEA-AEEA-OSu)-OtBu CAS No.: 1118767-17-1
C₂₀-OtBu-γ-Glu(OtBu)-AEEA-AEEA-OH
C₂₀-OtBu-γ-Glu(OtBu)-AEEA-AEEA-OH CAS No.: 1188328-37-1
C₂₀-γ-Glu(AEEA-AEEA-OSu)-OH
C₂₀-γ-Glu(AEEA-AEEA-OSu)-OH CAS No.: 1188328-38-2
Boc-Tyr(tBu)-Aib-OH
Boc-Tyr(tBu)-Aib-OH CAS No.: 2639221-78-4
Fmoc-Ile-Aib-OH
Fmoc-Ile-Aib-OH CAS No.: 2171139-20-9
Boc-Tyr(tBu)-Aib-Glu(OtBu)-Gly-OH
Boc-Tyr(tBu)-Aib-Glu(OtBu)-Gly-OH CAS No.: 2682040-93-1
Fmoc-Ala-Pro-OH
Fmoc-Ala-Pro-OH CAS No.: 186023-44-9
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  • Sherry Wu
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Why is L-Alanyl-L-tyrosine used in chemically defined media?

This dipeptide offers a stable and more soluble source of tyrosine, which is often limited in standard formulations due to solubility issues. It helps maintain consistent amino acid availability, supporting efficient protein synthesis and improving cell growth in tightly controlled media environments.

What roles do amino acids play in cell culture media?

Amino acids are essential building blocks for protein synthesis and act as key intermediates in numerous metabolic pathways. In cell culture, they are vital for promoting growth, supporting cell division, and maintaining cellular homeostasis. Proper amino acid supplementation ensures high viability, accelerates proliferation, and boosts experimental reproducibility.

How is glycylglycine (a dipeptide) used in the pharmaceutical and biotech industries?

Glycylglycine is commonly used to:

  • Enhance the uptake of amino acids in cell culture environments
  • Support the formulation of specialized medical and nutritional products
  • Serve as a substrate in enzymatic assays for dipeptidase activity
  • Act as an absorption enhancer in oral drug delivery systems to improve bioavailability

Why is S-sulfo-L-cysteine sodium salt added to mammalian cell culture media?

This amino acid derivative is chosen for its excellent solubility at neutral pH, making it suitable for feed strategies during high-density cultivation. It minimizes localized pH shifts and prevents thermal stress during buffer adjustments. Its use improves media preparation efficiency and supports higher protein expression in recombinant systems.

Which amino acids are beneficial for liver support?

  • Branched-chain amino acids (BCAAs) aid in liver regeneration and help manage symptoms of hepatic encephalopathy.
  • Glutamine contributes to gut barrier function and supports amino acid metabolism.
  • Arginine assists in detoxifying ammonia through the urea cycle.
    If you're looking for a formulation to improve liver function, feel free to reach out to our specialists for tailored guidance.

How can cell growth rate and survival be improved in culture?

Supplementing media with L-Tyrosine can help reduce oxidative stress and support healthier cell growth. It is especially important in serum-free or chemically defined media and is widely used in monoclonal antibody production, particularly with CHO and hybridoma cells.

What impact do amino acids have on mammalian cell behavior?

Beyond protein synthesis, amino acids are involved in signal transduction, membrane integrity, and cellular defense. Their metabolic fate influences energy balance, redox status, and the synthesis of critical cellular components, directly affecting cell health, productivity, and adaptability.

What is the role of L-Tyrosine in CHO cell culture?

L-Tyrosine plays a key role in the synthesis of structural proteins and enzymes. In CHO cell media, it enhances biomass production and supports robust cell growth, making it a critical supplement in biopharmaceutical manufacturing where consistent yields are required.

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Amino Acids & Derivatives for Cell Culture
  • L-Tyrosine
  • L-Tyrosine disodium salt
  • N-Acetyl-L-tryptophan
  • N-Acetyl-DL-tryptophan
  • L-Cystine dihydrochloride
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Amino Acids & Derivatives for Peptide Synthesis
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Sherry Wu
info@cd-bsx.com
+86-28-88531548
+86-13730848292