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L-Aspartic acid monosodium salt monohydrate

Amino Acids & Derivatives for Cell Culture

L-Aspartic acid monosodium salt monohydrate

Used in cell culture media for supporting cell growth and proliferation

L-Aspartic acid monosodium salt monohydrate (CAS No. 323194-76-9) is a white crystalline powder with a molecular weight of 173.10 g/mol and a melting point of approximately 140 °C. Used as a component in cell culture media, it supports cellular energy metabolism by participating in the synthesis of key intermediates that fuel cell growth and division.

We manufacture up to 10 tons per month to ensure consistent supply for high-demand applications. This amino acid derivative is delivered in 25 kg fiber drums and should be stored at –20 °C under an inert atmosphere to maintain its stability.

  • CAS No.: 323194-76-9
  • Molecular Formula: C₄H₈NNaO₅
  • Purity: 99% min
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  • Appearance White crystalline powder
  • Molecular Weight 173.10 g/mol
  • Density N/A
  • Boiling Point N/A
  • Melting Point ~140 °C (decomposition)
  • Flash Point N/A
  • Packaging 25 kg per fibre drum
  • Storage Conditions Store at –20 °C in a freezer, under inert atmosphere
  • Product Name
    1. L-Aspartic acid sodium salt monohydrate;
    2. Sodium aspartate monohydrate;
    3. (S)-2-Aminobutanedioic acid sodium salt;
    4. sodium;(2S)-2-amino-4-hydroxy-4-oxobutanoate;hydrate;
    5. L-Aspartic acid monosodium salt monohydrate
  • Production capacity 10 tons/month
  • Applications Raw material for cell culture media
Amino Acids & Derivatives for Cell Culture
Amino Acids & Derivatives for Cell Culture
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  • info@cd-bsx.com
  • Sherry Wu
  • +86-13730848292

How does L-Aspartic acid monosodium salt support energy metabolism in cell culture?

This amino acid salt acts as a metabolic precursor involved in energy production pathways. It helps cells generate the intermediates needed for ATP synthesis and contributes to efficient nutrient utilization, especially under high-growth or energy-demanding conditions

What roles do amino acids play in cell culture media?

Amino acids are essential building blocks for protein synthesis and act as key intermediates in numerous metabolic pathways. In cell culture, they are vital for promoting growth, supporting cell division, and maintaining cellular homeostasis. Proper amino acid supplementation ensures high viability, accelerates proliferation, and boosts experimental reproducibility.

How is glycylglycine (a dipeptide) used in the pharmaceutical and biotech industries?

Glycylglycine is commonly used to:

  • Enhance the uptake of amino acids in cell culture environments
  • Support the formulation of specialized medical and nutritional products
  • Serve as a substrate in enzymatic assays for dipeptidase activity
  • Act as an absorption enhancer in oral drug delivery systems to improve bioavailability

Why is S-sulfo-L-cysteine sodium salt added to mammalian cell culture media?

This amino acid derivative is chosen for its excellent solubility at neutral pH, making it suitable for feed strategies during high-density cultivation. It minimizes localized pH shifts and prevents thermal stress during buffer adjustments. Its use improves media preparation efficiency and supports higher protein expression in recombinant systems.

Which amino acids are beneficial for liver support?

  • Branched-chain amino acids (BCAAs) aid in liver regeneration and help manage symptoms of hepatic encephalopathy.
  • Glutamine contributes to gut barrier function and supports amino acid metabolism.
  • Arginine assists in detoxifying ammonia through the urea cycle.
    If you're looking for a formulation to improve liver function, feel free to reach out to our specialists for tailored guidance.

How can cell growth rate and survival be improved in culture?

Supplementing media with L-Tyrosine can help reduce oxidative stress and support healthier cell growth. It is especially important in serum-free or chemically defined media and is widely used in monoclonal antibody production, particularly with CHO and hybridoma cells.

What impact do amino acids have on mammalian cell behavior?

Beyond protein synthesis, amino acids are involved in signal transduction, membrane integrity, and cellular defense. Their metabolic fate influences energy balance, redox status, and the synthesis of critical cellular components, directly affecting cell health, productivity, and adaptability.

What is the role of L-Tyrosine in CHO cell culture?

L-Tyrosine plays a key role in the synthesis of structural proteins and enzymes. In CHO cell media, it enhances biomass production and supports robust cell growth, making it a critical supplement in biopharmaceutical manufacturing where consistent yields are required.

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Amino Acids & Derivatives for Cell Culture
  • L-Tyrosine
  • L-Tyrosine disodium salt
  • N-Acetyl-L-tryptophan
  • N-Acetyl-DL-tryptophan
  • L-Cystine dihydrochloride
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Amino Acids & Derivatives for Peptide Synthesis
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Sherry Wu
info@cd-bsx.com
+86-28-88531548
+86-13730848292