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  • Fmoc-L-Glu(OtBu)-OH
Fmoc-L-Glu(OtBu)-OH

Amino Acids & Derivatives for Peptide Synthesis

Fmoc-L-Glu(OtBu)-OH

Fmoc-L-Glu(OtBu)-OH (CAS No. 71989-18-9) is a protected glutamic acid derivative used in solid-phase peptide synthesis. The Fmoc group on the α-amino terminus and the tert-butyl ester on the side-chain carboxyl allow for controlled, stepwise coupling. This structure makes it suitable for synthesizing complex peptides such as Semaglutide and Tirzepatide. With a molecular formula of C₂₄H₂₇NO₆ and a molecular weight of 425.5 g/mol, it is provided as a white powder with 99% min purity and should be stored sealed in a cool, dry place.

  • CAS No.: 71989-18-9
  • Molecular Formula: C₂₄H₂₇NO₆
  • Purity: 99% min
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  • Appearance White powder
  • Molecular Weight 425.5 g/mol
  • Density 1.2 ± 0.1 g/cm³
  • Boiling Point 633.5 ± 55.0 °C at 760 mmHg
  • Melting Point 83–90 °C
  • Flash Point 337.0 ± 31.5 °C
  • Packaging 25 kg / fibre drum
  • Storage Conditions Store in a sealed, dry, cool place
  • Customs Code 29242970
  • Production Capacity 3 ton/month
  • Applications Raw material for GLP-1 peptides, polypeptides, Semaglutide, and Tirzepatide
  • Product Name
    1. Fmoc-Glu(OtBu)-OH;
    2. Fmoc-L-glutamic acid 5-tert-butyl ester;
    3. (S)-2-((((9H-Fluoren-9-yl)methoxy)carbonyl)amino)-5-(tert-butoxy)-5-oxopentanoic acid;
    4. (2S)-2-(9H-fluoren-9-ylmethoxycarbonylamino)-5-[(2-methylpropan-2-yl)oxy]-5-oxopentanoic acid;
    5. N-Fmoc-L-glutamic acid 5-tert-butyl ester;
    6. (2S)-5-(tert-butoxy)-2-({[(9H-fluoren-9-yl)methoxy]carbonyl}amino)-5-oxopentanoic acid;
    7. L-glutamic acid, N-[(9H-fluoren-9-ylmethoxy)carbonyl]-, 5-(1,1-dimethylethyl) ester
Amino Acids & Derivatives for Cell Culture
Amino Acids & Derivatives for Cell Culture
Amino Acids & Derivatives for Cell Culture
  • Related Amino Acids
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Product Name
CAS No.
  • Fmoc-Arg(pbf)-OH 154445-77-9
  • Fmoc-L-His(Trt)-OH 109425-51-6
  • Fmoc-Gly-OH 29022-11-5
  • Fmoc-L-Glu(OtBu)-OH 71989-18-9
  • Fmoc-L-Thr(tBu)-OH 71989-35-0
  • Fmoc-L-Phe-OH 35661-40-6
  • Fmoc-L-Ser(tBu)-OH 71989-33-8
  • Fmoc-L-Asp(OtBu)-OH 71989-14-5
  • Fmoc-L-Leu-OH 35661-60-0
  • Fmoc-L-Lys(Boc)-OH 71989-26-9
  • Fmoc-L-Gln(Trt)-OH 132327-80-1
  • Fmoc-L-Met-OH 71989-28-1
  • Fmoc-L-Ala-OH 35661-39-3
  • Fmoc-L-Val-OH 68858-20-8
  • Fmoc-L-Ile-OH 71989-23-6
  • Fmoc-Gln-OH 71989-20-3
  • Fmoc-Aib-OH 94744-50-0
  • Fmoc-L-Trp(Boc)-OH 143824-78-6
  • Fmoc-L-Asn(Trt)-OH 132388-59-1
  • Fmoc-L-Pro-OH 71989-31-6
  • Fmoc-L-Cys(Trt)-OH 103213-32-7
  • Fmoc-L-Tyr(tBu)-OH 71989-38-3
  • Boc-L-Lys(Z)-OH 2389-45-9
  • Boc-Lys(Ivdde)-OH 862847-44-7
  • H-Lys(Ivdde)-OH 919281-76-8
  • Fmoc-Lys(Ivdde)-OH 204777-78-6
  • Boc-Lys(dde)-OH 444795-66-8
Product Name
CAS No.
  • Fmoc-Lys(dde)-OH 150629-67-7
  • H-Lys(Boc)-OH 2418-95-3
  • BOC-L-Lysine 13734-28-6
  • Fmoc-Ala-Gly-OH 116747-54-7
  • Boc-Gly-Pro-OH 14296-92-5
  • Fmoc-Val-Gly-OH 142810-19-3
  • Fmoc-Pro-Pro-OH 129223-22-9
  • Fmoc-Glu(OtBu)-Phe-OH 1122076-55-4
  • H-Lys(Z)-OBzL.HCl 6366-70-7
  • Fmoc-D-Arg(Pbf) 187618-60-0
  • H-Gln(Trt)-OH 102747-84-2
  • N₆-Cbz-L-Lysine 1155-64-2
  • H-Ser(tBu)-OH 18822-58-7
  • H-Glu(OtBu)-OH 2419-56-9
  • H-Tyr(tBu)-OH 18822-59-8
  • H-Asp(OtBu)-OH 3057-74-7
  • H-Thr(tBu)-OH 4378-13-6
  • Boc-Glycine 4530-20-5
  • Boc-D-Arg HCl 35897-34-8
  • Boc-D-Arg HCl.H2O 113712-06-4
  • Boc-L-Leu.H2O 131139-15-6
  • Boc-Glycine tert-butyl ester 111652-20-1
  • Z-Gln(Trt)-OH 132388-60-4
  • Boc-beta-Alanine 3303-84-2
  • Boc-L-Pyroglutamic acid ethyl ester/Boc-Pyr-Oet 144978-12-1
  • Boc-L-Pyroglutamic acid methyl ester 108963-96-8
  • Boc-Arg(NO₂)-OH 2188-18-3
Glycylglycine
Glycylglycine CAS No.: 556-50-3
Triglycine
Triglycine CAS No.: 139-13-9
Ala-Ala-Ala
Ala-Ala-Ala CAS No.: 5874-90-8
L-Alanyl-L-cystine
L-Alanyl-L-cystine CAS No.: 115888-13-6
L-Alanyl-L-tyrosine
L-Alanyl-L-tyrosine CAS No.: 3061-88-9
Glycyl-L-tyrosine
Glycyl-L-tyrosine CAS No.: 658-79-7
Glycyl-L-tyrosine dihydrate
Glycyl-L-tyrosine dihydrate CAS No.: 39630-46-1
L-Alanyl-L-Glutamine
L-Alanyl-L-Glutamine CAS No.: 39537-23-0
L-Carnosine
L-Carnosine CAS No.: 305-84-0
Glycyl-L-glutamine monohydrate
Glycyl-L-glutamine monohydrate CAS No.: 13115-71-4
N,N'-Di-L-lysyl-L-cystine dihydrochloride
N,N'-Di-L-lysyl-L-cystine dihydrochloride CAS No.: 2920735-07-3
α-Ketoglutaric acid
α-Ketoglutaric acid CAS No.: 328-50-7
AEEA-AEEA
AEEA-AEEA CAS No.: 1143516-05-5
AEEA
AEEA CAS No.: 134978-97-5
Fmoc-AEEA-OH
Fmoc-AEEA-OH CAS No.: 166108-71-0
Fmoc-AEEA-AEEA
Fmoc-AEEA-AEEA CAS No.: 560088-89-3
Boc-AEEA-AEEA
Boc-AEEA-AEEA CAS No.: 1069067-08-8
18-(tert-Butoxy)-18-oxooctadecanoic acid
18-(tert-Butoxy)-18-oxooctadecanoic acid CAS No.: 843666-40-0
20-(tert-Butoxy)-20-oxoicosanoic acid
20-(tert-Butoxy)-20-oxoicosanoic acid CAS No.: 683239-16-9
H-Glu-OtBu
H-Glu-OtBu CAS No.: 45120-30-7
Fmoc-Lys-OH
Fmoc-Lys-OH CAS No.: 105047-45-8
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Peptides are used in treating viral infections such as hepatitis, HIV, and SARS. Some can target cancer cells by binding to specific tumor markers or mimicking signaling molecules. Others are derived from natural sources to address cardiovascular conditions, offering a wide range of therapeutic potential.

How do researchers select amino acids when designing peptides?

Longer peptides tend to be more difficult to purify and synthesize due to lower yield and stability. In these cases, auxiliary amino acids may be added at the ends to improve solubility and handling. For shorter peptides, typically under five residues, adding hydrophobic amino acids can enhance structural integrity and functionality.

What role do bioactive peptides play in the food industry?

Bioactive peptides are gaining popularity in functional food and nutrition sectors. These peptides can help regulate physiological processes, support immune health, and delay the onset of chronic diseases. Common sources include dairy proteins, plant extracts, collagen, and marine or animal-derived peptides.

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